China National Petroleum Corporation initiated technological innovation system construction in 2006.Following the principle of innovation-driven development, CNPC formulated the technology innovation strategy of the core technology-leading and defined three strategic objectives, which is keeping leading position in the superior technology areas, realizing great-leap-forward development in the catching-up areas, and occupying the cutting-edge technologies in the emerging and reserved areas. CNPC’s technological management shifted from focusing on R&D to full process including R&D, demonstration and deployment. The construction of technological innovation system mainly consisted of R&D portfolio management, restructuring R&D organization, technology facility improvement, management mechanism optimization, which has developed a series of core technologies, significantly boosted CNPC’s indigenous innovation capability and international competitiveness, meanwhile has strongly supported and led its main businesses.